Joint Genomic Center at Sofia University
Joint Genome Center Ltd is a specialized unit providing training and services in conducting molecular-biological analyzes in the field of omics-technologies.
The qualification of human resources includes academic and non-academic staff, scientific and administrative staff.
Acad. Atanas Atanasov
Assoc. Prof. Ivelin Panchev
Assoc. Prof. Krasimir Rusanov
Assoc. Prof. Ilian Badzhakov
Dr. Gorica Rachelova
Dr. Ivaila Dineva
JGC has state-of-the-art equipment in the field of omic technology - mass spectral analysis; qualitative and quantitative metabolite analysis by a gas chromatograph with a massive detector (triple quadrupole) Agilent Technologies 7000A; direct DNA sequencing and DNA fragment analysis (Sanger), providing a wide range of applications of molecular markers in genotyping, biodiversity assessment, mapping, etc., genetic analysis by real-time sequencing of PCR products - pyrosequenation, SNP and mutation analysis, quantitative analysis of CpG methylation. Used equipment is a new generation - DNA quenching robots (Quigen), Conventional PCR (LKB), Applied Biosystems, Horizontal and Vertical Gel Electrophoresis Systems and Photo-Gel (2- D DIGE scanner, Typhoon T94600, GE Healthcare), a UV-VIS spectrophotometer to measure samples with volumes of 2-50 μl. Device management, data acquisition and processing use specialized software. The accompanying laboratory equipment is of high class.
The Center offers high-tech services to solve key issues. In the field of genomics: - Analysis of the presence of genetically modified organisms (GMOs); • Identification of microorganisms based on sequencing of short specific plots; • Specialized product control analyzes focusing on issues of economic importance, DNA identification of crops and breeds of origin and purity; • Diagnosis and assessment of genetic status, etc. In the field of metabolomics: • Target analysis of metabolites - Quantitative determination of specific metabolites; • Metabolic profile • Qualitative and quantitative determination of a group of related compounds or compounds from a specific metabolic pathway • Qualitative and quantitative determination of all metabolites; • Fingerprint • Classification of samples by rapid and general analysis without detailed identification of the compounds.
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